This session will demonstrate a dialogue between a mental health professional and patient with complex symptomatology, including anxiety disorders, bipolar disorder with psychotic features, substance abuse, and posttraumatic stress disorder. The dialogue will focus on how to teach patients the relationship of neurobiology and psychopharmacology with symptom management while ascertaining their lived experience. This session will anchor symptoms in a neurobiological frame of reference to facilitate patient understanding that it is possible to learn to manage symptoms. Mr. Arauz and Dr. Moller will demonstrate how motivational interviewing techniques encourage patients to articulate their lived experience and connect symptoms with their neurobiological origins.